The Katy Trail State Park runs through Defiance near the Missouri River. This was the final home of frontiersman Daniel Boone, who settled in the Femme Osage Valley in 1799 after receiving a Spanish land grant. The hamlet was not named during Boone’s life.
Historic Defiance, MO is on Highway 94, 9 miles South of I-64/40. It is only 15 to 20 minutes from West St. Louis County and even closer to the major cities in St. Charles County. Located on the KATY Trail State Park , it attracts bikers and hikers, as well as visitors to the Wineries, Restaurants, Nurseries, B & Bs, Shops and many near by St. Charles County Parks.
Population: 155
Zip Code: 63341
School District: Francis Howell School District, Washington School District
Median Sales Price: $308,004
